A field experiment was conducted at CCS Haryana Agricultural University Regional Research Station, Karnal during rabi 2007-08 and 2008-09 to evaluate the efficacy of sulfosulfuron tank mixed with carfentrazoneethyl against weeds in wheat. The treatments included tank-mix or sequential application of sulfosulfuron 25 g/ha with carfentrazone 20, 15 and 10 g/ha, alone application of sulfosulfuron 25 g/ha and carfentrazone 20 g/ha, sequential application of clodinafop 60 g/ha or sulfosulfuron 25 g/ha with metsulfuron 4 g/ha, sulfosulfuron+metsulfuron (ready-mix) 32 g/ha, pinoxaden 50 g/ha fb carfentrazone 20 g/ha, mesosulfuron+iodosulfuron (ready-mix) 14.4 g/ha, along with weed free and weedy checks. Tank mix or sequential application of sulfosulfuron with carfentrazone being at par reduced the density and dry weight of Phalaris minor similar to sulfosulfuron alone, mesosulfuorn+iodosulfuron, sulfosulfuron+metsulfuron (ready-mix) and sulfosulfuron fb metsulfuron during both the years and it was as good as weed free check during 2008-09. All the tank-mix and sequential applications of sulfosulfuron with carfentrazone were at par with carfentrazone alone and similar to weed free check in respect of density and dry weight of broadleaf weeds. Tank-mix and sequential application of sulfosulfuron with carfentrazone were at par with sulfosulfuron alone, all other check herbicidal treatments (except carfentrazone alone being inferior) and weed free check in respect of effective tillers and grain yield of wheat. There was no phytotoxicity of combination treatments of sulfosulfuron with carfentrazone except some brown freckles appearing on the leaves due to tank-mix treatments or carfentrazone alone, which disappeared within two weeks without any adverse effect on the crop. Hence, carfentrazone was found compatible with sulfosulfuron as tank mixture against complex weed flora in wheat with no loss of herbicidal efficacy.