A research trial was carried out over the course of two years in Kharif  (rainy) season of 2021 and 2022 at the Agronomic Research Farm of the Faculty of Agriculture, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Wadura, India to study the bio-efficacy of imazethapyr as post-emergent herbicide at 25 days after sowing to control weeds and yield of common bean. The herbicide was applied at different doses i.e. 25, 50, 75, 100 and 125 g/ha and were compared under randomized completely block design. Application of imazethapyr 75-125 g/ha remarkably decreased the weed density and the weed biomass. The growth and yield parameters were significantly higher with imazethapyr 100 g/ha and were at par to 2 manual weeding. The common bean seed yield was reduced by 67.91% and 72.11% in 2021 and 2022, respectively, due to weed infestation in weedy check plots. Maximum weed control efficiency and index was obtained with application of imazethapyr 125 g/ha. However, imazethapyr 100 to 125 g/ha resulted in considerably higher benefit: cost ratios of 2.52 (2021) and 2.7 (2022) followed by imazethapyr 75 g/ha with benefit: cost ratios of 2.45 (2021) and 2.6 (2022). The results lead to the conclusion that imazethapyr application 100 g/ha as post-emergent herbicide applied at 25 days after sowing was found efficient for weed control with economically higher seed yield of common bean.