A field study was carried out at AICRP-WM Farm, B. A. College of Agriculture, Anand Agricultural University, Anand, India during two consecutive Rabi (winter) seasons of 2019-20 and 2020-21 to assess the effect of weed control measures on weeds and yield of Rabi maize. The field experiment was laid out in randomized block design having ten treatments and replicated thrice. The pre-emergence application (PE) of either atrazine + pendimethalin (tank-mix) 500 + 250 g/ha) or early post-emergence application (EPoE) at 10-15 days after seeding (DAS) of topramezone 336 + atrazine 25.2 + 500 g/ha (tank-mix) or tembotrione + atrazine 120 + 500 g/ha (tank-mix) provided effective control of both monocot and dicot weeds with higher yield and benefit cost ratio in winter maize during both the years. However, the mechanical weed control treatments, inter-culturing (IC) + hand weeding (HW) at 20 and 40 DAS provided effective control of weeds with higher grain yield of maize and higher benefit cost ratio during both the study years.