A field study was conducted during rainy (Kharif) seasons of 2019, 2020 and 2021 at S.G. College of Agriculture and Research Station, IGKV, Jagdalpur, Chhattisgarh to identify effective and economical weed management measure in dry direct-seeded rice in view of the importance of weeds in successful direct-seeded rice production. Hand weeding twice at 20 and 40 days after seeding (DAS) led to significant reduction of grassy, broad-leaved weeds and sedges and was at par with post-emergence application (PoE) of ethoxysulfuron 18 g/ha. Hand weeding twice at 20 and 40 DAS has significantly increased the tillers/m2, panicles/m2, seeds/panicle, 1000 seed weight and grain yield of dry direct-seeded rice. Both bispyribac-Na 25 g/ha PoE and pyrazosulfuron 25 g/ha PoE were as effective as hand weeding twice at 20 and 40 DAS in attaining higher weed control efficiency, enhancing rice growth parameters and yield of dry direct-seeded rice.