A field study was conducted for two years during Rabi season of 2012-13 and 2013-14 on the  fields of farmers’ of Jhunjhunu and Bikaner districts infested with broomrape (Orobanche) to test the efficiency of herbicides in mustard crop under AICRP on Weed Management at Agriculture Research Station, Swami Keshwanand Rajasthan Agricultural University, Bikaner. The experiment comprising ten weed control treatments consisting of neem cake (200 kg/ha) + pendimethalin 1.0 kg/ha, neem cake (200 kg/ha) + glyphosate 25 g/ha at 25 DAS, pendimethalin  0.75 kg/ha + glyphosate 35 g/ha + 55 g/ha at 25 and 55 DAS, pendimethalin 1.0 kg/ha, glyphosate 25 g/ha + 50 g/ha at 25 and 55 DAS, glyphosate 50 g/ha + 50 g/ha at 25 and 55 DAS, oxyfluorfen (200 g/ha), imazethapyr (20 g/ha), manual weeding and weedy check in a randomized block design with three replications. Among the different herbicides, application of glyphosate at 25 g/ha + 50 g/ha at 25 and 55 DAS  controlled broomrape effectively with nil phytotoxicity and produced significantly the highest seed yield in mustard during both the years over all the other herbicidal treatments.