A field experiment was conducted during Kharif 2016 and 2017 at Zonal Agriculture Research Station, V.C. Farm, Mandya (Southern dry Zone, Karnataka) to study the efficacy of various weed management practices on weeds in transplanted rice. The experiment consists of ten treatments replicated thrice in a randomized complete block design. Among the various treatments, significantly the lowest weed density (18.3-22.0 no./m2) and weed biomass (5.4-6.3 g/m2) was noticed with hand weeding at 25 and 45 DAS, which was at par with pre-emergence application (PE) of bensulfuron-methyl + pretilachlor fb triafamone + ethoxysulfuron applied at 30 days after transplanting (DAT). Weed management with bensulfuron-methyl + pretilachlor (60 + 600 g/ha) PE fb triafamone + ethoxysulfuron (60 g/ha) applied at 25 DAT recorded significantly higher paddy grain and straw yields and higher economic returns.