A field experiment was conducted at Regional Research and Technology Transfer Station, Chiplima, Odisha, India during the winter (Rabi) seasons of 2019-20 and 2020-21 to study the effect of sole and sequential application of herbicides for weed management in blackgram (Vigna mungo L.). The treatment combinations consisted pre-emergence herbicides, viz. pendimethalin and oxyfluorfen and post-emergence herbicides, viz. imazethapyr and clodinafop-propargyl + acifluorfen (ready-mix) in different rates along with weed free and weedy check. The weed competition resulted in 37.6% yield loss in blackgram. The pre-emergence application (PE) of oxyfluorfen 200 g/ha at 1 days after seeding (DAS) followed by (fb) post-emergence application of imazethapyr75 g/ha at 20 DAS caused 89.5% reduction in weed biomass with higher weed control efficiency (89.4%) and blackgram yield (0.77 t/ha). The net return ( 24.9 x 103/ha) and benefit: cost ratios (2.0) were also higher with this treatment and hence be recommended in West Central Table Land Zone of Odisha for better weed control, seed yield and higher economic returns in blackgram.